The Sexes: Gents & Ladies
Vaccination Protocol

As with many topics concerning dogs, therein lies controversy. Unfortunately, establishing a safe and effective vaccination protocol for a healthy breeding program is not saved from debate.  However, at Amatras, we  strive to stay up-to-date with the most recent advances in canine infectious diseases and their control and follow closely the advice recommended by the International Veterinary Information Service, in Ithaca, New York, in conjunction with our veterinarian.
There are currently 16 vaccinations in the United States that guard against various types of viral and bacterial infections, including a new vaccination to protect against a specific parasite. Here, I will concentrate on core and non-core vaccines that are most typically administered.

Core Vaccines - Program C - Maximal Approach (IVIS)







Recommended by IVIS:

9-11 wks, 12-14 wks


9 wks, 12 wks, 1 yr, 3 yrs

> 7 yr




Recommended by IVIS:

6-8 wks, 9-11 wks, 12-14 wks,  1 yr, 3 yrs


6 wks, 9 wks, 12 wks, 1 yr, 3 yrs

> 7 yr




Recommended by IVIS:

6-8 wks, 9-11 wks, 12-14 wks,  1 yr, 3 yrs


6 wks, 9 wks, 12 wks, 1 yr, 3 yrs

> 7 yr




Recommended by IVIS:

12-14 wks, 1 yr, 3 yrs


16 wks, 1 yr, 3 yrs

> 3 yr


Non-Core Vaccines - Program E - Moderate Approach (IVIS)

"Give only if the dog is at high risk and then only the vaccine that is needed."






Recommended by IVIS:

6-+ wks, annually - 1 dose


9 wks, 12 wks, 1 yr, 3 yrs

< 1 yr



[See CAV-2]




Recommended by IVIS:

12 wks & 14-15 wks - 2 doses Lepto

(2- or 4-serovars), annually


[We no longer administer Lepto due to risk of death by administering this shot]





Recommended by IVIS:

9-11 wks, 12-14 wks, annually


9 wks, 12 wks, 1 yr, 3 yrs

> 3 yr


MLV=Modified Live Vaccine; K=Killed Vaccine; KR=Killed Recombinant

Vaccines are given in full doses.

Notes about adverse reactions: Bacterial vaccines are more likely to cause immune-mediated reactions than do viral vaccines. Killed vaccines, especially those which contain adjuvants, are more likely to cause adverse reactions than do modified live vaccines. Because immune mediated reactions are genetically determined, some breeds, especially certain families of dogs, are at much greater risk to develop certain adverse reactions. Source: IVIS

We use Intervet Vaccines

Progard Puppy-DPv:  Canine Distemper, Parvovirus, (modified live virus)

(Given at 6-9-12 wks, 1 yr, every 3 yrs)


Progard-KC Plus: Canine Adenovirus Type 2, Parainfluenza, Bordetella Bronchiseptica Vaccine, (modified live virus and avirulent live culture)

(Given at 9-12 wks, 1 yr, every 3 yrs)


Rabies (administered by a licensed veterinarian)

(Given at 16 wks, 1 yr, every 3 yrs)


Core Vaccines

* Required by the State of Florida pursuant to F.S. 828.29.

* Adenovirus Type II (CAV-2)

Adenoviridae/Viral (MLV, K)

A viral infection or mild respiratory tract infection transmitted through contact with nasal secretions. This virus can also cause or contribute to canine infectious tracheobronchitis, or kennel cough. This virus manifests in the same way as parainfluenza virus and is treated in the same fashion.

Symptoms: fever, nasal discharge & coughing. Mild &/or short duration (6 days). Incubation period is approimately nine days. Adenovirus type 2 protects against canine infectious hepatitis caused by Canine Adenovirus Type 1 (CAV-1) without cuasing adverse reactions associated with CAV-1 (such as "blue eye").


* Distemper (CDV)

Paramyxovirdae/Viral (MLV)

A viral infection transmitted by direct or indirect contact with eye & nose discharges from an infected dog. Virus can be carried by air currents & inanimate objects, as well as urine/fecal material and is a serious disease that can affect dogs of all ages. Seen most often in puppies 3-6 months old; the primary killer of pups. Widespread, highly contagious, & often deadly.

Vaccine/Prevention: Most veterinarians recommend vaccinating puppies at five to six weeks of age using a combination canine distemper-measles-parainfluenza vaccine. The rationale for combining distemper and measles vaccines is that a high percentage of six-week-old puppies do not get a satisfactory response from the distemper vaccine alone because of maternal antibodies that neutralize the distemper antigen. The measles virus, which is quite similar to the distemper virus, can overcome maternal antibody interference and induce partial distemper protection. Alternatively, if maternal antibodies have actually disappeared in the six-week-old puppy, the distemper portion of the vaccine will induce complete protection.

Symptoms: Early signs begins as a cold with the first stage presenting a fever, poor appetite, vomiting, weigh loss, diarrhea,  listlessness and a watery discharge and/or squinting of the eyes. The second stage may involve neurological signs, such as paralysis and muscle twitching, head shaking and chewing movements followed by epileptic seizures.

Treatment: Involves giving electrolyte fluids, dietary supplements and anti-convulsants. Antibiotics may be prescribed to treat common secondary bacterial infections, such as pneumonia. Treatment of a dog showing neurological signs is largely unsuccessful.


* Canine Parvovirus-2 (CPV-2)

Parvoviridae/Viral (MLV, K)

Highly contagious and resistant virus, especially dangerous to puppies, withstands extreme temperature changes and exposure to most disinfectants. Can persist in the environment for months, but primarily affects dogs under one year of age. Transmitted by feces & transported on the hair or feet of infected dogs. It is also resistant to high temperatures and many disinfectants; however household bleach may be effective given in 1:30 solution on grounds. The parvovirus attacks the intestinal tract, white blood cells causing gastrointestinal upset, & may inflame the heart muscle (myocarditis). Some dogs may have parvo and never show any clinical signs. However, these dogs can still spread the virus to other dogs.  Death occurs within 48-72 hours after onset of symptoms.

Vaccine/Prevention: Even after a pup has received his first series of vaccinations, he should not be exposed to dogs that may be a source of infection until after he receives his final vaccination at 16 weeks of age. Annual boosters are required to maintain immunity.

Symptoms: Severe bloody diarrhea, vomiting, loss of appetite, depression, & high fever. Infected pups may act depressed, collapse, gasping for breath, & death may follow immediately.

Treatment: Onset is rapid, and the morbidity and mortality are very high. Fluid therapy with electrolytes are usually combined with antibiotics and symptomatic therapy.


* Rabies Virus (RV)

Rhabdoviridae/Viral (K)

The most feared disease, and is almost always fatal in animals and humans. Rabies is mainly spread through bites from infected animals, since it is mainly shed in the saliva, an acute viral encephalomyelitis (affecting the brain) and central nervous system. After entering the muscle cells, the virus replicates itself, and travels via the peripheral nerves to the spinal cord, and ascends to the brain. From here it once again travels through the peripheral nerves to the salivary glands. The clinical signs usually begin to appear 14 to 90 days after the dog is infected and once evident, the disease is invariably fatal by then. The disease typically has three phases: prodromal state, excitatory, and paralytic and two manifestations: furious form and paralytic form.

Furious Form: This is the classical Mad Dog Syndrome. The animal becomes irrational and with the slightest provocation, viciously and aggressively uses its teeth and claws to attack. The posture gives an appearance of alertness or anxiety with dilated pupils. Lack of muscular coordination and seizures develop. Death is the result of progressive paralysis.

Paralytic Form: This presents with paralysis of the throat and muscles of the jaw, with profuse salivation and inability to swallow. The lower jaw drops down. The paralysis progresses to all parts of the body and coma and death follow quickly.

Symptoms: Signs may include nervousness, paralysis, excessive salivation, hyper-excitability, increased aggression, and other behavioural changes. 


Non-Core Vaccines

* Required by the State of Florida pursuant to F.S. 828.29.

* Adenovirus Type I & Hepatitis (CAV-1 & ICH)

Viral (K)

Hepatitis is a highly contagious virus caused by Adenovirus Type-1 and attacks the liver. Transmitted through contact with contaminated objects such as urine, saliva, and feces. Recovered dogs may shed the virus in their urine for over six months.

Vaccine: Hepatits vaccines containing CAV-1 caused clouding of the clear window of the eye (called "blue eye") two weeks after vaccination, and are no longer used. Hepatitis Vaccine is incorporated into the DHPP shot which is given at 3ith to 12 weeks of age and again at 16 weeks of age. Annual vaccination is recommended, although initial immunity may persist for life.

Symptoms: Early signs are similar to distemper. Other symptoms may include a whiteness or cloudiness of the eye. Another strain of the same virus causes respiratory tract infections. 

Treatment: Extensive fluid therapy, broad spectrum antibiotics and symptomatic treatment is given.


* Bordetellosis, B. Bronchiseptica

Bacterial (MLV, K)

Better known as Kennel Cough. It is a bacterial respiratory tract infection transmitted by nasal secretions caused by the bacterium Bordetella Bronchiseptica, Adenovirus 1 & 2, and Parainfluenza. Harsh, non productive cough may last 1-3 weeks. Symptoms include: harsh, nonproductive severe cough lasting 1-3 weeks. Cough is stimulated by physical exertion or touching the throat area. Self-limiting unless pneumonia develops. Bordetella can occur alone or in combination with other respiratory problems.


Borreliosis (Lyme Disease)

Bacterial (K, KR)

Bacterial infection caused by a bite from an infected tick. Symptoms include fever, lethargy, muscle stiffness. Lameness can occur in more severe cases.


Canarypox-Distemper Virus

Viral (LRV)

Similar to Canine Distemper Virus.


Coronvirus Enteritis (CCV)

Viral (MLV, K)

A highly contagious virus, seen most often in young puppies, but mild and self-limiting intestinal disease that occasionally, but will rarely cause death. The virus involves the stomach and intestines, mostly in young pups. Can set dogs up for more severe cases of Parvo.

Vaccines/Prevention: Vaccination against coronavirus does not prevent the disease, but may reduce the severity of the illness. Puppies should be vaccinated at 12 weeks of age and again at 16 weeks. Unvaccinated adults should receive two vaccinations four weeks apart. Annual boosters are required.

Symptoms: Diarrhea (yellow or mixed with blood), vomiting, listlessness, depression, loss of appetite. Dogs can suffer for several days to several weeks. Highly contagious.

Treatment: Fluid therapy, electrolytes and antibiotics are used to treat the symptoms.



Parasite (K)

A waterborne protozoa parasite found in pounds, puddles, swimming pools and in the backyard. Giardia is transmitted to other animals by feces. Causes gastrointestinal problems in dogs. Symptoms can include diarrhea, weight loss, abdominal pain and vomiting.


* Leptospirosis (CL)

Bacterial (K/4)

Lepto is an infectious bacterial disease transmitted by contact with urine. Can be spread to humans as well as other animals and may lead to permanent kidney damage. There are four strains of this bacteria: canicola, girppotyphosa, icterohaemorrhagiae, and pomona .

Vaccine/Prevention: Leptospira bacterin protects against two of the four subspecies of bacteria that cause leptospirosis. The bacterin is incorporated into a DHLPP shot given at 12 weeks of age and again at 16 weeks of age. Leptospira bacterin is responsible for 70% of post-vaccination DHLPP anaphylactic shock reactions. In addition, the vaccine currently available does not protect against hte two species that are currently responsible for the majority of cases. Immunity following vaccination averages about four to six months.

Symptoms: A hunched gait because of pain in the kidneys, formation of ulcers in the mouth and tongue, bleeding from the mouth, passage of bloody stools and severe thirst with increased urination are the main symptoms. Other symptoms may include: high fever, depression, jaundice, vomiting, impaired vision, and convulsions. Incubation period 5-15 days.

Treatment: Fluid therapy and broad spectrum antibiotics. It is found that dogs which have been vaccinated, still get affected sometimes.



Viral  (MLV)

Similar to Canine Distemper Virus.


* Parainfluenza (CPI)

Paramyxoviridae/Viral (MLV)

This virus is one cause of canine infectious tracheobronchitis, which affects the respiratory tract (also known as kennel cough). The virus affects dog five days after exposure, Clinical signs can persist for as little as three-seven days and up to three weeks. Puppies may acquire a serious bronchopneumonia and debilitated adult dogs or older dogs may develop chronic bronchitis. The disease is spread through close contact of dogs through close contact with respiratory secretions. Stress may also precipitate development of the disease.

Symptoms: Harsh, dry cough with possibly gagging/retching of various intensity and frequency, and fever; in more severe cases: anorexia, nasal discharge, productive cough and depression along with a secondary bacterial infection cause more severe manifestation.

Treatment: There is no specific anti-viral treatment, but daily nursing care, environment stabilization and possibly cough suppressants, along with antibiotics to control secondary bacterial infections may reduce and control symptoms.



There are many diseases in which a vaccination has not yet been developed. Just because your dog has received his immunizations does not mean he cannot contract a variety of illnesses or other infectious diseases, for an animal is still just as vulnerable as a human being to these outside organisms.


Other Bacterial Diseases

Bacteria are single-celled germs.


Tetanus (Lockjaw)




Coliobacillosis (E. Coli)


Other Viral Diseases

Viruses are the tiniest germs known, more basic than cells.

Canine Herpesvirus Infection



Fungal Diseases

Many types of fungi spread via airborne spores.







Protozoan Diseases

Single-celled organisms that are usually carried in water.





Canine Babesiosis ( Nantucket Disease)

Canine Hepatozoonosis

American Trypanosomiasis (Chagas Disease)


Rickettsial Diseases

Disease-causing bacteria carried as parasites by fleas, ticks and lice.

Canine Ehrlichiosis

Rocky Mountain Spotted Fever

Canine Salmon Poisoning Disease


For more detailed information on vaccinations, visit:

International Veterinary Information Service


For more detailed information on other infectious diseases, we recommend:

Dog Owner's Home Veterinary Handbook

by James M. Giffin, MD & Liisa D. Carlson, DVM]


Amatras Shelties

321 S. McCall Road

Englewood, FL 34223


Tel. 941.460.8505

Fax. 941.460.8506

Call or write to set an appointment


Companion and conformation (show) shelties are guaranteed against genetic defects that render them unsuitable as a family companion for one year with a full money-back guarantee.

(Beyond one year of age, a five-year guarantee is extended with offer of a replacement puppy.)


Amatras Shetland Sheepdogs work purposefully with Sheltie breeders that perpetuate longevity & health in their lineage.

The family lineages you find throughout this website represent some of the finest lineages that have been offered to us and to the Shetland Sheepdog breed.

Thus, our goal is to perpetuate the quality already established and continually strive for the betterment of the breed.  



Amatras are breeders dedicated to focusing on longevity, health, temperament, structure, brains and beauty. Dogs are added to the program with these qualities only and bred only to improve each trait through each successive generation.




© Amatras Shetland Sheepdogs

Englewood, Florida

Established 2000.